I was making my bed with fresh clean sheets yesterday, and as I raised the mattress, a spider ran out from under the mattress and up the side. I
However, protected or not, spiders are NOT allowed in my bed.
I brushed the spider off the bed and it ran under the roll top desk. I didn't pursue it.
There are plenty of flies around here for it to munch on, so I am sure it didn't mind relocating... at least not mind so much that it comes back stalking me in the night.